Often I encounter rat infestations where the rats have gotten into a house and totally run amuck. People are usually worried about the feces they leave behind but rat urine can be equally as dangerous as the diseases in feces. When people come into contact with rat urine there is always the chance that they may pick up leptospirosis, a bacterial infection that can become a life-and-death issue. Leptospirosis is a bacterial disease spread in rat urine, not mice. Although some people who become infected with leptospirosis suffer no symptoms, others experience all kinds of symptoms, including: fever, headache, chills, muscle aches, vomiting, yellow skin and eyes, abdominal pain and rashes. The illness usually lasts from a couple days to three weeks or longer. Without treatment, recovery may take several months or in some cases become life-threatening through acute kidney and liver failure. It is advised people avoid contact with rats or places where rats might have urinated. If someone comes in contact with areas where rats might live, wash your hands with soap and water afterward.